GRANITERO (Granisetron) is an antiemetic drug. It works by blocking the action of a chemical messenger (serotonin) in the brain that can cause nausea and vomiting during cancer treatment (chemotherapy) or after surgery.
Granisetron selectively blocks serotonin 5-HT 3 receptors located at the ends of the vagus nerve and in the trigger zone of the fundus of the IV ventricle of the brain (practically does not affect other serotonin receptors). Granisetron is well absorbed in the gastrointestinal tract (if there is no vomiting). Binds to plasma proteins by 65%.
In the liver, granisetron undergoes N-demethylation and oxidation of the aromatic ring, after which it is conjugated. The resulting metabolites have antiserotonin activity. T 1/2 of granisetron with oral and / in the introduction is 9 hours, with wide individual variability. The main route of elimination of granisetron is with bile, about 12% (after intravenous administration) is excreted in the urine within 48 hours.
Granisetron eliminates vomiting that occurs when the parasympathetic nervous system is excited due to the release of serotonin from enterochromaffin cells.
Robert (verified owner) –
Best quality medicines,
Robert –
Cooper (verified owner) –
all types of supplements are available.
Cooper –
Hadleigh (verified owner) –
Ohhh what a product. I am really thankfull.
Hadleigh –
Kingston (verified owner) –
they were also very accurate regarding the time line for delivery.
Kingston –
Nicolas (verified owner) –
best online pharma product website.
Nicolas –
Adalee (verified owner) –
good
Adalee –
Cristina (verified owner) –
Wow! Wonderful experience with the company.
Cristina –
Emilio (verified owner) –
100% professionals. Good service.
Emilio –
Victor (verified owner) –
They keep Most of the general Pharma and super Speciality medicines.
Victor –
Wendy (verified owner) –
Wow! Wonderful experience with the company.
Wendy –
Lyra (verified owner) –
First class service and super fast shipping excellent products also
Lyra –
Nola (verified owner) –
Online medicine delivery firm with aim of different sense to serve people in efficiency manner.
Nola –
Emberly (verified owner) –
One fo the best organisation for anyone to get medicine on low price.
Emberly –
Evan (verified owner) –
One fo the best organisation for anyone to get medicine on low price.
Evan –
Noel (verified owner) –
Great services.
Noel –
Adrian (verified owner) –
Very fast n good service
Adrian –
Claudia (verified owner) –
Fast shipping , just received sofisbuvir and vrlpatasvir tablets .
Claudia –
Della (verified owner) –
I recently ordered some cancer Chemotherapy drugs to mydrughouse. The drugs were not expensive.
Della –
Joelle (verified owner) –
They are best service provider of quality affordable medicines in USA.
Joelle –
Gina (verified owner) –
They keep Most of the general Pharma and super Speciality medicines.
Gina –
Michaela (verified owner) –
Great costumer service.
Michaela –