PIRFENEX (PIRFENIDONE) attenuates fibroblast proliferation, production of fibrosis-related proteins and cytokines, and increases interstitial matrix biosynthesis and accumulation in response to cytokine growth factors such as transforming growth factor beta and platelet growth factor.
PIRFENEX (PIRFENIDONE) is a medicine used to treat idiopathic pulmonary fibrosis. It works by decreasing lung fibrosis by inhibiting the production of growth factors and procollagens I and II.
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