Viraday (Efavirenz Emtricitabine & Tenofovir) is a medicine used to treat HIV / AIDS. It is a fixed-dose combination of efavirenz, emtricitabine, and tenofovir disoproxil.
Efavirenz is an HIV-1 NNRTI. Efavirenz is a noncompetitive inhibitor of HIV-1 reverse transcriptase (RT) and has no significant inhibitory effect on HIV-2 RT and DNA polymerase (α, β, γ and δ) of human cells. Emtricitabine is a nucleoside analogue of cytidine and belongs to NRTIs.
Emtricitabine and tenofovir are phosphorylated by intracellular enzymes to form emtricitabine triphosphate and tenofovir diphosphate, respectively.